Browsing by Author "Kulan, Handan"
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Identification of critical proteins associated with learning process for Down syndrome
Kulan, Handan; Dağ, Tamer (Kadir Has Üniversitesi, 2020)DS protein profilleri laboratuvarda biyokimyasal teknikler uygulayarak gözlemlenmektedir. Fakat, elde edilen protein listesi uzundur ve listedeki her protein DS ile alakalı değildir. Bu yüzden, DS analizi ve tedavisinde, ... -
Importance of Regional Differences in Brain Throughout Aging for Down Syndrome
Kulan, Handan; Dağ, Tamer (Association for Computing Machinery, 2018)Down syndrome (DS) which affects approximately one in 700 live births is caused by an extra copy of the long arm of human chromosome 21 (HSA21). Statistical analysis has been done for understanding the protein expression ... -
In silico identification of critical proteins associated with learning process and immune system for Down syndrome
Kulan, Handan; Dağ, Tamer (Public Library Science, 2019)Understanding expression levels of proteins and their interactions is a key factor to diagnose and explain the Down syndrome which can be considered as the most prevalent reason of intellectual disability in human beings. ... -
Using machine learning classifiers to identify the critical proteins in Down syndrome
Kulan, Handan; Dağ, Tamer (Association for Computing Machinery, 2018)Pharmacotherapies of intellectual disability (ID) are largely unknown as the abnormalities at the complex molecular level which causes ID are difficult to understand. Down syndrome (DS) which is the prevalent cause of ID ...